B-hLTA/hTNFA/hLTB/hTNFR2/hTNFR1/hLTBR mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Humanized Mouse Models

Cytokine Humanized Mice

Text

B-hLTA/hTNFA/hLTB/hTNFR2/hTNFR1/hLTBR mice

Strain Name	C57BL/6-Lta^{tm1(LTA)Bcgen} Tnf^{tm1(TNF)Bcgen} Ltb^{tm1(LTB)Bcgen}Tnfrsf1b^{tm1(TNFRSF1B)Bcgen} Tnfrsf1a^{tm1(TNFRSF1A)Bcgen} Ltbr^{tm1(LTBR)Bcgen}/Bcgen	Common Name	B-hLTA/hTNFA/hLTB/hTNFR2/hTNFR1/hLTBR mice
Background	C57BL/6	Catalog number	113337
Related Genes	LT, TNFB, TNFSF1, TNLG1E; DIF-alpha, TNFA, TNFSF2, TNLG1F, TNF; TNFC, TNFSF3, TNLG1C, p33; CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR; CD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60; D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3;
NCBI Gene ID	16992, 21926, 16994, 21938, 21937, 17000

B-hLTA/hTNFA/hLTB/hTNFR2/hTNFR1/hLTBR mice were obtained by mating B-hLTA/hTNFA/hLTB mice (130769) and B-hTNFR2/hTNFR1/hLTBR mice (140801). For validation data of this mouse model, you can refer to the validation data from the related gene humanized mouse models.